Aurelia Butler

Researchers have designed smart, colour-controllable white light devices from quantum dots — tiny semiconductors just a few billionths of a metre in size — which are more efficient and have better colour saturation than standard LEDs, and can dynamically reproduce daylight conditions in a single light.
The researchers, from the University of Cambridge, designed the next-generation smart lighting system using a combination of nanotechnology, colour science, advanced computational methods, electronics and a unique fabrication process.
The team found that by using more than the three primary lighting colours used in typical LEDs, they were able to reproduce daylight more accurately. Early tests of the new design showed excellent colour rendering, a wider operating range than current smart lighting technology, and wider spectrum of white light customisation. The results are reported in the journal Nature Communications.
As the availability and characteristics of ambient light are connected with wellbeing, the widespread availability of smart lighting systems can have a positive effect on human health since these systems can respond to individual mood. Smart lighting can also respond to circadian rhythms, which regulate the daily sleep-wake cycle, so that light is reddish-white in the morning and evening, and bluish-white during the day.
When a room has sufficient natural or artificial light, good glare control, and views of the outdoors, it is said to have good levels of visual comfort. In indoor environments under artificial light, visual comfort depends on how accurately colours are rendered. Since the colour of objects is determined by illumination, smart white lighting needs to be able to accurately express the colour of surrounding objects. Current technology achieves this by using three different colours of light simultaneously.
Quantum dots have been studied and developed as light sources since the 1990s, due to their high colour tunability and colour purity. Due their unique optoelectronic properties, they show excellent colour performance in both wide colour controllability and high colour rendering capability. More

Scientists and engineers are constantly developing new materials with unique properties that can be used for 3D printing, but figuring out howto print with these materials can be a complex, costly conundrum.
Often, an expert operator must use manual trial-and-error — possibly making thousands of prints — to determine ideal parameters that consistently print a new material effectively. These parameters include printing speed and how much material the printer deposits.
MIT researchers have now used artificial intelligence to streamline this procedure. They developed a machine-learning system that uses computer vision to watch the manufacturing process and then correct errors in how it handles the material in real-time.
They used simulations to teach a neural network how to adjust printing parameters to minimize error, and then applied that controller to a real 3D printer. Their system printed objects more accurately than all the other 3D printing controllers they compared it to.
The work avoids the prohibitively expensive process of printing thousands or millions of real objects to train the neural network. And it could enable engineers to more easily incorporate novel materials into their prints, which could help them develop objects with special electrical or chemical properties. It could also help technicians make adjustments to the printing process on-the-fly if material or environmental conditions change unexpectedly.
“This project is really the first demonstration of building a manufacturing system that uses machine learning to learn a complex control policy,” says senior author Wojciech Matusik, professor of electrical engineering and computer science at MIT who leads the Computational Design and Fabrication Group (CDFG) within the Computer Science and Artificial Intelligence Laboratory (CSAIL). “If you have manufacturing machines that are more intelligent, they can adapt to the changing environment in the workplace in real-time, to improve the yields or the accuracy of the system. You can squeeze more out of the machine.”
The co-lead authors are Mike Foshey, a mechanical engineer and project manager in the CDFG, and Michal Piovarci, a postdoc at the Institute of Science and Technology in Austria. MIT co-authors include Jie Xu, a graduate student in electrical engineering and computer science, and Timothy Erps, a former technical associate with the CDFG. The research will be presented at the Association for Computing Machinery’s SIGGRAPH conference. More

A UBC Okanagan research team has created a computer modelling program to help scientists predict the effect of climate damage and eventual restoration plans on coral reefs around the globe.
This is a critical objective, says Dr. Bruno Carturan, because climate change is killing many coral species and can lead to the collapse of entire coral reef ecosystems. But, because they are so complex, it’s logistically challenging to study the impact of devastation and regeneration of coral reefs.
Real-world experiments are impractical, as researchers would need to manipulate and disrupt large areas of reefs, along with coral colonies and herbivore populations, and then monitor the changes in structure and diversity over many years.
“Needless to say, conducting experiments that will disturb natural coral reefs is unethical and should be avoided, while using big aquariums is simply unfeasible,” says Dr. Carturan, who recently completed his doctoral studies with the Irving K. Barber Faculty of Science. “For these reasons, no such experiments have ever been conducted, which has hindered our capacity to predict coral diversity and the associated resilience of the reefs.”
For his latest research, published recently in Frontiers in Ecology and Evolution, Dr. Carturan used models to create 245 coral communities, each with a unique set of nine species and each occupying a surface of 25 square metres. The model represents coral colonies and different species of algae that grow, compete and reproduce together while also being impacted by climate.
Crucially, he notes, all the key components of the model, including species’ traits such as competitive abilities and growth rates, are informed by pre-existing, real-world data from 800 species. More

Scientists at the University of Virginia School of Medicine and their collaborators have used DNA to overcome a nearly insurmountable obstacle to engineer materials that would revolutionize electronics.
One possible outcome of such engineered materials could be superconductors, which have zero electrical resistance, allowing electrons to flow unimpeded. That means that they don’t lose energy and don’t create heat, unlike current means of electrical transmission. Development of a superconductor that could be used widely at room temperature — instead of at extremely high or low temperatures, as is now possible — could lead to hyper-fast computers, shrink the size of electronic devices, allow high-speed trains to float on magnets and slash energy use, among other benefits.
One such superconductor was first proposed more than 50 years ago by Stanford physicist William A. Little. Scientists have spent decades trying to make it work, but even after validating the feasibility of his idea, they were left with a challenge that appeared impossible to overcome. Until now.
Edward H. Egelman, PhD, of UVA’s Department of Biochemistry and Molecular Genetics, has been a leader in the field of cryo-electron microscopy (cryo-EM), and he and Leticia Beltran, a graduate student in his lab, used cryo-EM imaging for this seemingly impossible project. “It demonstrates,” he said, “that the cryo-EM technique has great potential in materials research.”
Engineering at the Atomic Level
One possible way to realize Little’s idea for a superconductor is to modify lattices of carbon nanotubes, hollow cylinders of carbon so tiny they must be measured in nanometers — billionths of a meter. But there was a huge challenge: controlling chemical reactions along the nanotubes so that the lattice could be assembled as precisely as needed and function as intended.
Egelman and his collaborators found an answer in the very building blocks of life. They took DNA, the genetic material that tells living cells how to operate, and used it to guide a chemical reaction that would overcome the great barrier to Little’s superconductor. In short, they used chemistry to perform astonishingly precise structural engineering — construction at the level of individual molecules. The result was a lattice of carbon nanotubes assembled as needed for Little’s room-temperature superconductor.
“This work demonstrates that ordered carbon nanotube modification can be achieved by taking advantage of DNA-sequence control over the spacing between adjacent reaction sites,” Egelman said.
The lattice they built has not been tested for superconductivity, for now, but it offers proof of principle and has great potential for the future, the researchers say. “While cryo-EM has emerged as the main technique in biology for determining the atomic structures of protein assemblies, it has had much less impact thus far in materials science,” said Egelman, whose prior work led to his induction in the National Academy of Sciences, one of the highest honors a scientist can receive.
Egelman and his colleagues say their DNA-guided approach to lattice construction could have a wide variety of useful research applications, especially in physics. But it also validates the possibility of building Little’s room-temperature superconductor. The scientists’ work, combined with other breakthroughs in superconductors in recent years, could ultimately transform technology as we know it and lead to a much more “Star Trek” future.
“While we often think of biology using tools and techniques from physics, our work shows that the approaches being developed in biology can actually be applied to problems in physics and engineering,” Egelman said. “This is what is so exciting about science: not being able to predict where our work will lead.”
The work was supported by the Department of Commerce’s National Institute of Standards and Technology and by National Institutes of Health grant GM122510, as well as by an NRC postdoctoral fellowship. More

Ecologists won’t always need expensive and bulky equipment to measure vegetation in the wild. Rice University scientists have discovered a modern heads-up display works pretty well.
Rice researchers set up aMicrosoft HoloLens as a mixed-reality sensor to feed VegSense, their application to measure understory vegetation, plant life that grows between the forest canopy and floor.
A proof-of-concept study by graduate student Daniel Gorczynski and bioscientistLydia Beaudrot shows VegSense could be a suitable alternative to traditional classical field measurements at a low cost.
Their study in Methods in Ecology and Evolution shows the hardware-software combination excels at quantifying relatively mature trees in the wild, which is one measure of a forest’s overall health.
Gorczynski came up with the idea to try HoloLens, commonly marketed as a productivity tool for manufacturing, health care and education. He developed the open-source software for the device and noted that while the combination is less effective at picking up saplings and small branches, there’s ample room for improvement.
Gorczynski said he was introduced to mixed-reality sensing while an undergraduate at Vanderbilt University and recognized its potential for biological studies. “It seemed sort of like a natural fit,” he said. Gorczynski brought the idea to Beaudrot in 2019 shortly after his arrival at Rice. More

Using digital devices, such as smartphones, could help improve memory skills rather than causing people to become lazy or forgetful, finds a new study led by UCL researchers.
The research, published in Journal of Experimental Psychology: General, showed that digital devices help people to store and remember very important information. This, in turn, frees up their memory to recall additional less important things.
Neuroscientists have previously expressed concerns that the overuse of technology could result in the breakdown of cognitive abilities and cause “digital dementia.”
However, the findings show that using a digital device as external memory not only helps people to remember the information saved into the device, but it also helps them to remember unsaved information too.
To demonstrate this, researchers developed a memory task to be played on a touchscreen digital tablet or computer. The test was undertaken by 158 volunteers aged between 18 and 71.
Participants were shown up to 12 numbered circles on the screen, and had to remember to drag some of these to the left and some to the right. The number of circles that they remembered to drag to the correct side determined their pay at the end of the experiment. One side was designated ‘high value’, meaning that remembering to drag a circle to this side was worth 10 times as much money as remembering to drag a circle to the other ‘low value’ side. More

MRI, electroencephalography (EEG) and magnetoencephalography have long served as the tools to study brain activity, but new research from Carnegie Mellon University introduces a novel, AI-based dynamic brain imaging technology which could map out rapidly changing electrical activity in the brain with high speed, high resolution, and low cost. The advancement comes on the heels of more than thirty years of research that Bin He has undertaken, focused on ways to improve non-invasive dynamic brain imaging technology.
Brain electrical activity is distributed over the three-dimensional brain and rapidly changes over time. Many efforts have been made to image brain function and dysfunction, and each method bears pros and cons. For example, MRI has commonly been used to study brain activity, but is not fast enough to capture brain dynamics. EEG is a favorable alternative to MRI technology however, its less-than-optimal spatial resolution has been a major hindrance in its wide utility for imaging.
Electrophysiological source imaging has also been pursued, in which scalp EEG recordings are translated back to the brain using signal processing and machine learning to reconstruct dynamic pictures of brain activity over time. While EEG source imaging is generally cheaper and faster, specific training and expertise is needed for users to select and tune parameters for every recording. In new published work, He and his group introduce a first of its kind AI-based dynamic brain imaging methodology, that has the potential of imaging dynamics of neural circuits with precision and speed.
“As part of a decades-long effort to develop innovative, non-invasive functional neuroimaging solutions, I have been working on a dynamic brain imaging technology that can provide precision, be effective and easy to use, to better serve clinicians and researchers,” said Bin He, professor of biomedical engineering at Carnegie Mellon University.
He continues, “Our group is the first to reach the goal by introducing AI and multi-scale brain models. Using biophysically inspired neural networks, we are innovating this deep learning approach to train a neural network that can precisely translate scalp EEG signals back to neural circuit activity in the brain without human intervention.”
In He’s study, which was recently published in Proceedings of the National Academy of Sciences(PNAS), the performance of this new approach was evaluated by imaging sensory and cognitive brain responses in 20 healthy human subjects. It was also rigorously validated in identifying epileptogenic tissue in a cohort of 20 drug-resistant epilepsy patients by comparing AI based noninvasive imaging results with invasive measurements and surgical resection outcomes.
Results wise, the novel AI approach outperformed conventional source imaging methods when precision and computational efficiency are considered.
“With this new approach, you only need a centralized location to perform brain modeling and training deep neural network,” explained He. “After collecting data in a clinical or research setting, clinicians and researchers could remotely submit the data to the centralized well trained deep neural networks and quickly receive accurate analysis results. This technology could speed up diagnosis and assist neurologists and neurosurgeons for better and faster surgical planning.”
As a next step, the group plans to conduct larger clinical trials in efforts to bring the research closer to clinical implementation.
“The goal is for efficient and effective dynamic brain imaging with simple operation and low cost,” explained He. “This AI-based brain source imaging technology makes it possible.”
Story Source:
Materials provided by College of Engineering, Carnegie Mellon University. Original written by Sara Vaccar. Note: Content may be edited for style and length. More

Imagine stretching a piece of film to reveal a hidden message. Or checking an arm band’s color to gauge muscle mass. Or sporting a swimsuit that changes hue as you do laps. Such chameleon-like, color-shifting materials could be on the horizon, thanks to a photographic technique that’s been resurrected and repurposed by MIT engineers.
By applying a 19th-century color photography technique to modern holographic materials, an MIT team has printed large-scale images onto elastic materials that when stretched can transform their color, reflecting different wavelengths as the material is strained.
The researchers produced stretchy films printed with detailed flower bouquets that morph from warm to cooler shades when the films are stretched. They also printed films that reveal the imprint of objects such as a strawberry, a coin, and a fingerprint.
The team’s results provide the first scalable manufacturing technique for producing detailed, large-scale materials with “structural color” — color that arises as a consequence of a material’s microscopic structure, rather than from chemical additives or dyes.
“Scaling these materials is not trivial, because you need to control these structures at the nanoscale,” says Benjamin Miller, a graduate student in MIT’s Department of Mechanical Engineering. “Now that we’ve cleared this scaling hurdle, we can explore questions like: Can we use this material to make robotic skin that has a human-like sense of touch? And can we create touch-sensing devices for things like virtual augmented reality or medical training? It’s a big space we’re looking at now.”
The team’s results appear today in Nature Materials. Miller’s co-authors are MIT undergraduate Helen Liu, and Mathias Kolle, associate professor of mechanical engineering at MIT. More