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    Healthcare app reduces symptoms of COPD compared to regular treatment

    COPD is a common respiratory condition and one of the top causes of hospital admissions each year, particularly during winter months. In the UK it accounts for over 140,000 hospital admissions and one million bed days at a major cost to the NHS.
    At a time when fewer people are able to access face-to-face consultations with their GPs and elderly patients with conditions such as COPD need are shielding, these are very encouraging findings for the future of digital health services.
    In this new study, 41 patients admitted to hospital with severe exacerbations of COPD were allocated into two groups, with one group receiving their regular treatments and the second group of patients set up with access to the MyCOPD app as well as receiving treatment as usual.
    MyCOPD gives patients access to a broad range of services wherever they are in the world, without the need to travel to clinics or join waiting lists. These services include receiving education from medical experts, information on how factors such as pollen, pollution and the weather in their area could affect their condition and videos that demonstrate how to use inhalers correctly. Users also complete daily diaries of their symptoms and medication, which allows the app to help them identify when they are deteriorating and provide advice on appropriate courses of action.
    The results of this latest trial, published in the journal NPJ Digital Medicine, showed that over the course of three months, the number of further exacerbations within the group using the app was nearly half that for those who just received treatment as usual (18 compared to 34). Incorrect use of inhalers also reduced by around 80% for MyCOPD users, compared to a fall of around 30% for the control group.
    Significantly, the average age of participants using the app was over 65 and despite not being regular web users, all were able to adapt to the technology.
    MyCOPD, developed and hosted by my mhealth, is one of the largest apps of its kind and one of a small number of digital health apps with NICE approval. The Department for Health and Social Care highlighted it in their 2019 review into digital healthcare because of its potential to deliver better outcomes for patients and improve NHS productivity. Now this latest peer reviewed trial provides further evidence of its benefits.
    Professor Tom Wilkinson of the University of Southampton who developed the app and led the trial said, “COPD has a significant impact on peoples’ daily lives so we wanted to develop a means of healthcare that is like having an expert in your pocket; giving you advice whenever you need it.
    “The transition towards digital healthcare has been taking place for some time but has accelerated since the outbreak of COVID-19. Patients with conditions such as COPD can be particularly vulnerable now so it is important that we have evidence of the effectiveness of these technologies.
    “Hopefully the success of this will lead to further use and the development of similar products that allow patients to manage other conditions to further improve their wellbeing and reduce the burden on the NHS.”

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    Materials provided by University of Southampton. Note: Content may be edited for style and length. More

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    How frigid lizards falling from trees revealed the reptiles’ growing cold tolerance

    After the coldest night in south Florida in a decade, lizards were dropping out of palm trees, landing legs up. The scientists who raced to investigate the fallen reptiles have now found that, despite such graceless falls, some of these tropical, cold-blooded creatures are actually more resilient to cold than previously thought.
    The finding sheds light on how some species might respond to extreme weather events caused by human-caused climate change (SN: 12/10/19). Although climate change is expected to include gradual warming globally, scientists think that extreme events such as heat waves, cold snaps, droughts and torrential downpours could also grow in number and strength over time.
    The idea for the new study was born after evolutionary ecologist James Stroud received a photo of a roughly 60-centimeter-long iguana prone on its back on a sidewalk from a friend in Key Biscayne, an island town south of Miami. The previous night, temperatures dropped to just under 4.4° Celsius (40° Fahrenheit).
    “When air temperatures drop below a critical limit, lizards lose the ability to move,” says Stroud, of Washington University in St. Louis. Lizards that sleep in trees “may lose their grip.” Stunned lizards on the ground are likely easy prey for predators, he notes.

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    Realizing that the cold snap could be used to study how future instances of extreme weather might affect such animals in the wild, Stroud and colleagues rushed to collect live specimens of as many different kinds of lizards as they could in the Miami area (SN: 8/27/20). The researchers then tested how well the six reptile species they captured tolerated cold by sticking thermometers on the animals, placing them in a large cooler of ice and observing how cold they got before becoming too stunned to right themselves after getting flipped on their backs.
    Stroud and colleagues had previously run similar tests on these lizard species as part of research on invasive species. That work in 2016 suggested that the reptiles might not easily withstand cold snaps like the recent one — cold tolerances ranged from as low as about 7.7° C for the Puerto Rican crested anole (Anolis cristatellus) to roughly 11.1° C for the brown basilisk (Basiliscus vittatus).
    Some tropical, cold-blooded lizards, such as this brown basilisk (Basiliscus vittatus), are more resilient to cold than previously thought, a new study finds.John Sullivan/iNaturalist (CC BY-NC 4.0)
    The new study, however, revealed that the reptiles now could withstand temperatures roughly 1 to 4 degrees C colder. Oddly, the lizards, on average, could all endure cold down to the same lowest temperature, about 5.5° C, the researchers report in the October Biology Letters. Given the great variation in size, ecology and physiology between these species, “this was a really unexpected result,” and one that the researchers don’t have an explanation for, Stroud says.
    Natural selection may be behind the change, meaning that abnormally cold temperatures are killing off those individuals that could not survive and leaving behind those that happen to be better able to tolerate cold. Alternatively, the reptiles’ bodies could have changed in some way to acclimate to the colder temperatures. Stroud hopes in the future to measure the cold tolerance of lizards immediately before a forecasted cold snap and then examine the same reptiles immediately afterward to look for signs of acclimation.
    Scientists have long thought that tropical species, which have typically evolved in thermally stable environments, might prove especially vulnerable to major shifts in temperature (SN: 5/20/15). This new study reveals a way in which species can either rapidly evolve or acclimate, which “may provide ecosystems with some resilience to extreme climate events,” says Alex Pigot, an ecologist at University College London who did not take part in the research.
    One remaining question “is whether this resilience also applies to extreme heating events,” Pigot adds. “Previous evidence has suggested that species’ upper thermal limits may be less flexible than their lower thermal limits.” More

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    Evolution of consumption: A psychological ownership framework

    Researchers from Boston University, Rutgers University, University of Washington, Cornell University, and University of Pennsylvania published a new paper in the Journal of Marketing that proposes that preserving psychological ownership in the technology-driven evolution of consumption underway should be a priority for marketers and firm strategy.
    Why does — and what happens when — nothing feels like it is MINE?
    Technological innovations are rapidly changing the consumption of goods and services. Consumption is evolving in modern capitalist societies from a model in which people legally own private material goods to access-based models in which people purchase temporary rights to experiential goods owned by and shared with others. For example, many urban consumers have replaced car ownership with car and ride sharing services. Physical pictures occupying frames, wallets, and albums have been replaced with digital photographs that can be viewed at any time and songs, books, movies, or magazines can be pulled down from the cloud. Half the world population now buys, sells, generates, and consumes goods and information online through connected devices, generating vast quantities of personal data about their consumption patterns and private lives.
    The researchers say that technological innovations such as digitization, platform markets, and the exponential expansion of the generation and collection of personal data are driving an evolution in consumption along two major dimensions. The first dimension is from a model of legal ownership, where consumers purchase and consume their own private goods, to a model of legal access, in which consumers purchase temporary access rights to goods and services owned and used by others. The second dimension is from consuming solid material goods to liquid experiential goods. The benefits of these consumption changes, from convenience to lower economic cost to greater sustainability to better preference matching, makes legal ownership of many physical private goods undesirable and unnecessary. But their commensurate reduction in psychological ownership — the feeling that a thing is “MINE” — may have profoundly negative consequences for consumers and firms.
    Morewedge explains that “Psychological ownership is not legal ownership, but is, in many ways, a valuable asset for consumers and firms. It satisfies important consumer motives and is value-enhancing. The feeling that a good is MINE enhances how much we like the good, strengthens our attachment to it, and increases how much we think it is worth.” Downstream consequences to firms include increased consumer demand for goods and services offered by the firm, willingness to pay for goods, word of mouth, and loyalty.
    The researchers propose that the consumption changes underway can have three effects on psychological ownership — threaten it, cause it to transfer to other targets, and create new opportunities to preserve it. Fractional ownership models and the impermanence and intangibility of access-based experiential goods stunt the development of psychological ownership for streamed, rented, and cloud-based goods. In many cases, this results in a loss of psychological ownership, but sometimes it will transfer to the brands (e.g., Disney, Uber, MyChart) and devices through which goods and services are accessed (e.g., smartphones) or transfer to the community of consumers who use them (e.g., Facebook groups, followers, and forums). The greater choice and new channels for self-expression provided by this evolution of consumption, however, also offer new opportunities for consumers to feel as much psychological ownership for these access-based experiential goods and services they consume as they would for privately owned material goods.
    These consumption changes and their effects on psychological ownership appear in a framework that is examined across three macro marketing trends: (1) the growth of the sharing economy; (2) the digitization of goods and service; and (3) the expansion of personal data. Exemplary cases explored include ride sharing, the digitization of music, and the expansion of health and wellness data. Each case illustrates why each of these trends is eroding psychological ownership, how it is being transformed, and new opportunities being created for firms to recapture and preserve it — whether in goods and services, intermediary devices like a phone, or at the brand level.
    This psychological ownership framework generates future research opportunities and actionable marketing strategies for firms seeking to preserve the value-enhancing consequences of psychological ownership and navigate cases where it is a liability. It highlights many ways in which psychological ownership will continue to be a valuable lens through which to view, understand, forecast, and manage the consumer experience.

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    Materials provided by American Marketing Association. Original written by Matt Weingarden. Note: Content may be edited for style and length. More

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    Direction decided by rate of coin flip in quantum world

    Flip a coin. Heads? Take a step to the left. Tails? Take a step to the right. In the quantum world? Go in both directions at once, like a wave spreading out. Called the walker analogy, this random process can be applied in both classical and quantum algorithms used in state-of-the-art technologies such as artificial intelligence and data search processes. However, the randomness also makes the walk difficult to control, making it more difficult to precisely design systems.
    A research team based in Japan may be moving toward a more controlled walk by unveiling the mechanism underlying the directional decision of each quantum step and introducing a way to potentially control the direction of movement. They published their results on October 16 in Scientific Reports, a Nature Research journal.
    “In our study, we focused on the coin determining the behavior of the quantum walk to explore controllability,” said paper author Haruna Katayama, graduate student in the Graduate School of Integrated Arts and Sciences at Hiroshima University.
    In classical systems, the coin directs the walker in space: right or left. In quantum systems, a coin is infinitely less reliable, since the walker operates both as a particle stood in one space and as a wave stretched out in every possibility across time.
    “We introduced the time-dependent coin of which the probability of landing on heads or tails varies temporally for unveiling the function of the coin,” Katayama said.
    This time-dependent coin can shift the walker’s position, the researchers found, but the wave characteristic of the walker obscured how much physical space the coin controlled.
    “We succeeded in clarifying the equivalence of two completely different concepts — the equivalence of the rate of change in coin probability and the velocity of the wave — for the first time,” Katayama said. “This unveiled mechanism enables us to control the quantum walk on demand by manipulating the coin with preserving the random process, providing core fundamental elements of innovative quantum information processing technologies such as quantum computing.”
    The researchers determined that how quickly the coin flipped directly affected how quickly the wave moved, resulting in some control of the walker’s movement.
    “The walking mechanism enables us to tailor quantum walks as we desire by manipulating the coin flipping rate,” Katayama said. “In addition, we have found that the quantum walk with the desired trajectory can be realized on demand by designing the coin. Our results open the path towards the control of quantum walks.”

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    Materials provided by Hiroshima University. Note: Content may be edited for style and length. More

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    Early results from DETECT study suggest fitness trackers can predict COVID-19 infections

    Examining data from the first six weeks of their landmark DETECT study, a team of scientists from the Scripps Research Translational Institute sees encouraging signs that wearable fitness devices can improve public health efforts to control COVID-19.
    The DETECT study, launched on March 25, uses a mobile app to collect smartwatch and activity tracker data from consenting participants, and also gathers their self-reported symptoms and diagnostic test results. Any adult living in the United States is eligible to participate in the study by downloading the research app, MyDataHelps.
    In a study that appears today in Nature Medicine, the Scripps Research team reports that wearable devices like Fitbit are capable of identifying cases of COVID-19 by evaluating changes in heart rate, sleep and activity levels, along with self-reported symptom data — and can identify cases with greater success than looking at symptoms alone.
    “What’s exciting here is that we now have a validated digital signal for COVID-19. The next step is to use this to prevent emerging outbreaks from spreading,” says Eric Topol, MD, director and founder of the Scripps Research Translational Institute and executive vice president of Scripps Research. “Roughly 100 million Americans already have a wearable tracker or smartwatch and can help us; all we need is a tiny fraction of them — just 1 percent or 2 percent — to use the app.”
    With data from the app, researchers can see when participants fall out of their normal range for sleep, activity level or resting heart rate; deviations from individual norms are a sign of viral illness or infection.
    But how do they know if the illness causing those changes is COVID-19? To answer that question, the team reviewed data from those who reported developing symptoms and were tested for the novel coronavirus. Knowing the test results enabled them to pinpoint specific changes indicative of COVID-19 versus other illnesses.

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    “One of the greatest challenges in stopping COVID-19 from spreading is the ability to quickly identify, trace and isolate infected individuals,” says Giorgio Quer, PhD, director of artificial intelligence at Scripps Research Translational Institute and first author of the study. “Early identification of those who are pre-symptomatic or even asymptomatic would be especially valuable, as people may potentially be even more infectious during this period. That’s the ultimate goal.”
    For the study, the team used health data from fitness wearables and other devices to identify — with roughly 80% prediction accuracy — whether a person who reported symptoms was likely to have COVID-19. This is a significant improvement from other models that only evaluated self-reported symptoms.
    As of June 7, 30,529 individuals had enrolled in the study, with representation from every U.S. state. Of these, 3,811 reported symptoms, 54 tested positive for the coronavirus and 279 tested negative. More sleep and less activity than an individual’s normal levels were significant factors in predicting coronavirus infection.
    The predictive model under development in DETECT might someday help public health officials spot coronavirus hotspots early. It also may encourage people who are potentially infected to immediately seek diagnostic testing and, if necessary, quarantine themselves to avoid spreading the virus.
    “We know that common screening practices for the coronavirus can easily miss pre-symptomatic or asymptomatic cases,” says Jennifer Radin, PhD, an epidemiologist at the Scripps Research Translational Institute who is leading the study. “And infrequent viral tests, with often-delayed results, don’t offer the real-time insights we need to control the spread of the virus.”
    The DETECT team is now actively recruiting more participants for this important research. The goal to enroll more than 100,000 people, which will help the scientists improve their predictions of who will get sick, including those who are asymptomatic. In addition, Radin and her colleagues plan to incorporate data from frontline essential workers who are at an especially high risk of infection.
    Learn more about DETECT at detectstudy.org.
    The study, “Wearable Sensor Data and Self-reported Symptoms for COVID-19 Detection,” is authored by Giorgio Quer, Jennifer M. Radin, Matteo Gadaleta, Katie Baca-Motes, Lauren Ariniello, Edward Ramos, Vik Kheterpal, Eric J. Topol and Steven R Steinhubl.
    Funding for the research was provided by the National Center for Advancing Translational Sciences at the National Institutes of Health [UL1TR00255]. More

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    Corporations directing our attention online more than we realize

    It’s still easy to think we’re in control when browsing the internet, but a new study argues much of that is ‘an illusion.’ Corporations are ‘nudging’ us online more than we realize, and often in hidden ways. Researchers analyzed click-stream data on a million people over one month of internet use to find common browsing sequences, then connected that with site and platform ownership and partnerships, as well as site design and other factors. More

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    Trust levels in AI predicted by people's relationship style

    A University of Kansas interdisciplinary team led by relationship psychologist Omri Gillath has published a new paper in the journal Computers in Human Behavior showing people’s trust in artificial intelligence (AI) is tied to their relationship or attachment style.
    The research indicates for the first time that people who are anxious about their relationships with humans tend to have less trust in AI as well. Importantly, the research also suggests trust in artificial intelligence can be increased by reminding people of their secure relationships with other humans.
    Grand View Research estimated the global artificial-intelligence market at $39.9 billion in 2019, projected to expand at a compound annual growth rate of 42.2% from 2020 to 2027. However, lack of trust remains a key obstacle to adopting new artificial intelligence technologies.
    The new research by Gillath and colleagues suggests new ways to boost trust in artificial intelligence.
    In three studies, attachment style, thought to play a central role in romantic and parent-child relationships, was shown also to affect people’s trust in artificial intelligence. Some of the research’s key findings:
    People’s attachment anxiety predicts less trust in artificial intelligence.
    Enhancing attachment anxiety reduced trust in artificial intelligence.

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    Conversely, enhancing attachment security increases trust in artificial intelligence.

    These effects are unique to attachment security and were not found with exposure to positive affect cues.
    “Most research on trust in artificial intelligence focuses on cognitive ways to boost trust. Here we took a different approach by focusing on a ‘relational affective’ route to boost trust, seeing AI as a partner or a team member rather than a device,” said Gillath, professor of psychology at KU.
    “Finding associations between one’s attachment style — an individual difference representing the way people feel, think and behave in close relationships — and her trust in AI paves the way to new understandings and potentially new interventions to induce trust.”
    The research team includes investigators from a wide array of disciplines, including psychology, engineering, business and medicine. This interdisciplinary approach provides a new perspective on artificial intelligence, trust and associations with relational and affective factors.
    “The findings show you can predict and increase people’s trust levels in non-humans based on their early relationships with humans,” Gillath said. “This has the potential to improve adoption of new technologies and the integration of AI in the workplace.”

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    Materials provided by University of Kansas. Note: Content may be edited for style and length. More