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    AI has no idea what it’s doing, but it’s threatening us all

    The age of artificial intelligence (AI) has transformed our interactions, but threatens human dignity on a worldwide scale, according to a study led by Charles Darwin University (CDU).
    Study lead author Dr Maria Randazzo, an academic from CDU’s School of Law, found the technology was reshaping Western legal and ethical landscapes at unprecedented speed but was undermining democratic values and deepening systemic biases.
    Dr Randazzo said current regulation failed to prioritize fundamental human rights and freedoms such as privacy, anti-discrimination, user autonomy, and intellectual property rights – mainly thanks to the untraceable nature of many algorithmic models.
    Calling this lack of transparency a “black box problem,” Dr Randazzo said decisions made by deep-learning or machine-learning processes were impossible for humans to trace, making it difficult for users to determine if and why an AI model has violated their rights and dignity and seek justice where necessary.
    “This is a very significant issue that is only going to get worse without adequate regulation,” Dr Randazzo said.
    “AI is not intelligent in any human sense at all. It is a triumph in engineering, not in cognitive behavior.
    “It has no clue what it’s doing or why – there’s no thought process as a human would understand it, just pattern recognition stripped of embodiment, memory, empathy, or wisdom.”
    Currently, the world’s three dominant digital powers – the United States, China, and the European Union – are taking markedly different approaches to AI, leaning on market-centric, state-centric, and human-centric models respectively.

    Dr Randazzo said the EU’s human-centric approach is the preferred path to protect human dignity but without a global commitment to this goal, even that approach falls short.
    “Globally, if we don’t anchor AI development to what makes us human – our capacity to choose, to feel, to reason with care, to empathy and compassion – we risk creating systems that devalue and flatten humanity into data points, rather than improve the human condition,” she said.
    “Humankind must not be treated as a means to an end.”
    “Human dignity in the age of Artificial Intelligence: an overview of legal issues and regulatory regimes” was published in the Australian Journal of Human Rights.
    The paper is the first in a trilogy Dr Randazzo will produce on the topic. More

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    Scientists just found a hidden quantum geometry that warps electrons

    How can data be processed at lightning speed, or electricity conducted without loss? To achieve this, scientists and industry alike are turning to quantum materials, governed by the laws of the infinitesimal. Designing such materials requires a detailed understanding of atomic phenomena, much of which remains unexplored. A team from the University of Geneva (UNIGE), in collaboration with the University of Salerno and the CNR-SPIN Institute (Italy), has taken a major step forward by uncovering a hidden geometry — until now purely theoretical — that distorts the trajectories of electrons in much the same way gravity bends the path of light. This work, published in Science, opens new avenues for quantum electronics.
    Future technologies depend on high-performance materials with unprecedented properties, rooted in quantum physics. At the heart of this revolution lies the study of matter at the microscopic scale — the very essence of quantum physics. In the past century, exploring atoms, electrons and photons within materials gave rise to transistors and, ultimately, to modern computing.
    New quantum phenomena that defy established models are still being discovered today. Recent studies suggest the possible emergence of a geometry within certain materials when vast numbers of particles are observed. This geometry appears to distort the trajectories of electrons in these materials — much like Einstein’s gravity bends the path of light.
    From theory to observation
    Known as quantum metric, this geometry reflects the curvature of the quantum space in which electrons move. It plays a crucial role in many phenomena at the microscopic scale of matter. Yet detecting its presence and effects remains a major challenge.
    ”The concept of quantum metric dates back about 20 years, but for a long time it was regarded purely as a theoretical construct. Only in recent years have scientists begun to explore its tangible effects on the properties of matter,” explains Andrea Caviglia, full professor and director of the Department of Quantum Matter Physics at the UNIGE Faculty of Science.
    Thanks to recent work, the team led by the UNIGE researcher, in collaboration with Carmine Ortix, associate professor in the Department of Physics at the University of Salerno, has detected quantum metric at the interface between two oxides — strontium titanate and lanthanum aluminate — a well-known quantum material. ”Its presence can be revealed by observing how electron trajectories are distorted under the combined influence of quantum metric and intense magnetic fields applied to solids,” explains Giacomo Sala, research associate in the Department of Quantum Matter Physics at the UNIGE Faculty of Science and lead author of the study.
    Unlocking Future Technologies
    Observing this phenomenon makes it possible to characterise a material’s optical, electronic and transport properties with greater precision. The research team also demonstrates that quantum metric is an intrinsic property of many materials — contrary to previous assumptions.
    ”These discoveries open up new avenues for exploring and harnessing quantum geometry in a wide range of materials, with major implications for future electronics operating at terahertz frequencies (a trillion hertz), as well as for superconductivity and light-matter interactions,” concludes Andrea Caviglia. More

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    Strange “heavy” electrons could be the future of quantum computing

    Osaka, Japan — A joint research team from Japan has observed “heavy fermions,” electrons with dramatically enhanced mass, exhibiting quantum entanglement governed by the Planckian time – the fundamental unit of time in quantum mechanics. This discovery opens up exciting possibilities for harnessing this phenomenon in solid-state materials to develop a new type of quantum computer.
    Heavy fermions arise when conduction electrons in a solid interact strongly with localized magnetic electrons, effectively increasing their mass. This phenomenon leads to unusual properties like unconventional superconductivity and is a central theme in condensed matter physics. Cerium-Rhodium-Tin (CeRhSn), the material studied in this research, belongs to a class of heavy fermion systems with a quasi-kagome lattice structure, known for its geometrical frustration effects.
    Researchers investigated the electronic state of CeRhSn, known for exhibiting non-Fermi liquid behavior at relatively high temperatures. Precise measurements of CeRhSn’s reflectance spectra revealed non-Fermi liquid behavior persisting up to near room temperature, with heavy electron lifetimes approaching the Planckian limit. The observed spectral behavior, describable by a single function, strongly indicates that heavy electrons in CeRhSn are quantum entangled.
    Dr. Shin-ichi Kimura of The University of Osaka, who led the research, explains, “Our findings demonstrate that heavy fermions in this quantum critical state are indeed entangled, and this entanglement is controlled by the Planckian time. This direct observation is a significant step towards understanding the complex interplay between quantum entanglement and heavy fermion behavior.”
    Quantum entanglement is a key resource for quantum computing, and the ability to control and manipulate it in solid-state materials like CeRhSn offers a potential pathway towards novel quantum computing architectures. The Planckian time limit observed in this study provides crucial information for designing such systems. Further research into these entangled states could revolutionize quantum information processing and unlock new possibilities in quantum technologies. This discovery not only advances our understanding of strongly correlated electron systems but also paves the way for potential applications in next-generation quantum technologies. More

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    New AI model predicts which genetic mutations truly drive disease

    When genetic testing reveals a rare DNA mutation, doctors and patients are frequently left in the dark about what it actually means. Now, researchers at the Icahn School of Medicine at Mount Sinai have developed a powerful new way to determine whether a patient with a mutation is likely to actually develop disease, a concept known in genetics as penetrance.
    The team set out to solve this problem using artificial intelligence (AI) and routine lab tests like cholesterol, blood counts, and kidney function. Details of the findings were reported in the August 28 online issue of Science. Their new method combines machine learning with electronic health records to offer a more accurate, data-driven view of genetic risk.
    Traditional genetic studies often rely on a simple yes/no diagnosis to classify patients. But many diseases, like high blood pressure, diabetes, or cancer, don’t fit neatly into binary categories. The Mount Sinai researchers trained AI models to quantify disease on a spectrum, offering more nuanced insight into how disease risk plays out in real life.
    “We wanted to move beyond black-and-white answers that often leave patients and providers uncertain about what a genetic test result actually means,” says Ron Do, PhD, senior study author and the Charles Bronfman Professor in Personalized Medicine at the Icahn School of Medicine at Mount Sinai. “By using artificial intelligence and real-world lab data, such as cholesterol levels or blood counts that are already part of most medical records, we can now better estimate how likely disease will develop in an individual with a specific genetic variant. It’s a much more nuanced, scalable, and accessible way to support precision medicine, especially when dealing with rare or ambiguous findings.”
    Using more than 1 million electronic health records, the researchers built AI models for 10 common diseases. They then applied these models to people known to have rare genetic variants, generating a score between 0 and 1 that reflects the likelihood of developing the disease.
    A higher score, closer to 1, suggests a variant may be more likely to contribute to disease, while a lower score indicates minimal or no risk. The team calculated “ML penetrance” scores for more than 1,600 genetic variants.
    Some of the results were surprising, say the investigators. Variants previously labeled as “uncertain” showed clear disease signals, while others thought to cause disease had little effect in real-world data.

    “While our AI model is not meant to replace clinical judgment, it can potentially serve as an important guide, especially when test results are unclear. Doctors could in the future use the ML penetrance score to decide whether patients should receive earlier screenings or take preventive steps, or to avoid unnecessary worry or intervention if the variant is low-risk,” says lead study author Iain S. Forrest, MD, PhD, in the lab of Dr. Do at the Icahn School of Medicine at Mount Sinai. “If a patient has a rare variant associated with Lynch syndrome, for instance, and it scores high, that could trigger earlier cancer screening, but if the risk appears low, jumping to conclusions or overtreatment might be avoided.”
    The team is now working to expand the model to include more diseases, a wider range of genetic changes, and more diverse populations. They also plan to track how well these predictions hold up over time, whether people with high-risk variants actually go on to develop disease, and whether early action can make a difference.
    “Ultimately, our study points to a potential future where AI and routine clinical data work hand in hand to provide more personalized, actionable insights for patients and families navigating genetic test results,” says Dr. Do. “Our hope is that this becomes a scalable way to support better decisions, clearer communication, and more confidence in what genetic information really means.”
    The paper is titled “Machine learning-based penetrance of genetic variants.”
    The study’s authors, as listed in the journal, are Iain S. Forrest, Ha My T. Vy, Ghislain Rocheleau, Daniel M. Jordan, Ben O. Petrazzini, Girish N. Nadkarni, Judy H. Cho, Mythily Ganapathi, Kuan-Lin Huang, Wendy K. Chung, and Ron Do.
    This work was supported in part by the following grants: National Institute of General Medical Sciences of the National Institutes of Health (NIH) (T32-GM007280); the National Institute of General Medical Sciences of the NIH (R35-GM124836); the National Institute of Diabetes and Digestive and Kidney Diseases (U24-DK062429); the National Human Genome Research Institute of the NIH (R01-HG010365); the National Institute of General Medical Sciences of the NIH (R35-GM138113); and the National Institute of Diabetes and Digestive and Kidney Diseases (U24-DK062429).
    * Mount Sinai Health System member hospitals: The Mount Sinai Hospital; Mount Sinai Brooklyn; Mount Sinai Morningside; Mount Sinai Queens; Mount Sinai South Nassau; Mount Sinai West; and New York Eye and Ear Infirmary of Mount Sinai More

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    Scientists create scalable quantum node linking light and matter

    Quantum networks are often described as the future of the internet — but instead of transmitting classical information in bits, they send quantum information carried by photons. These networks could enable ultra-secure communication, link together distant quantum computers into a single, vastly more powerful machine, and create precision sensing systems that can measure time or environmental conditions with unprecedented accuracy.
    To make such a network possible, so-called quantum network nodes — that can store quantum information and share it via light particles – are needed. In their latest work, the Innsbruck team led by Ben Lanyon at the Department of Experimental Physics of the University of Innsbruck demonstrated such a node using a string of ten calcium ions in a prototype quantum computer. By carefully adjusting electric fields, the ions were moved one by one into an optical cavity. There, a finely tuned laser pulse triggered the emission of a single photon whose polarization was entangled with the ion’s state.
    The process created a stream of photons; each tied to a different ion-qubit in the register. In future the photons could travel to distant nodes and be used to establish entanglement between separate quantum devices. The researchers achieved an average ion-photon entanglement fidelity of 92 percent, a level of precision that underscores the robustness of their method.
    “One of the key strengths of this technique is its scalability,” says Ben Lanyon. “While earlier experiments managed to link only two or three ion-qubits to individual photons, the Innsbruck setup can be extended to much larger registers, potentially containing hundreds of ions and more.” This paves the way for connecting entire quantum processors across laboratories or even continents.
    “Our method is a step towards building larger and more complex quantum networks,” says Marco Canteri, the first author of the study. “It brings us closer to practical applications such as quantum-secure communication, distributed quantum computing and large-scale distributed quantum sensing.”
    Beyond networking, the technology could also advance optical atomic clocks, which keep time so precisely that they would lose less than a second over the age of the universe. Such clocks could be linked via quantum networks to form a worldwide timekeeping system of unmatched accuracy.
    The work, now published in Physical Review Letters, was financially supported by the Austrian Science Fund FWF and the European Union, among others, and demonstrates not only a technical milestone but also a key building block for the next generation of quantum technologies. More

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    A strange quantum effect could power future electronics

    Researchers at Rice University and collaborating institutions have discovered direct evidence of active flat electronic bands in a kagome superconductor. This breakthrough could pave the way for new methods to design quantum materials — including superconductors, topological insulators and spin-based electronics — that could power future electronics and computing technologies. The study, published in Nature Communications Aug. 14, centers on the chromium-based kagome metal CsCr₃Sb₅, which becomes superconducting under pressure.
    Kagome metals, characterized by their two-dimensional lattices of corner-sharing triangles, have recently been predicted to host compact molecular orbitals, or standing-wave patterns of electrons that could potentially facilitate unconventional superconductivity and novel magnetic orders that can be made active by electron correlation effects. In most materials, these flat bands remain too far from active energy levels to have any significant impact; however, in CsCr₃Sb₅, they are actively involved and directly influence the material’s properties.
    Pengcheng Dai, Ming Yi and Qimiao Si of Rice’s Department of Physics and Astronomy and Smalley-Curl Institute, along with Di-Jing Huang of Taiwan’s National Synchrotron Radiation Research Center, led the study.
    “Our results confirm a surprising theoretical prediction and establish a pathway for engineering exotic superconductivity through chemical and structural control,” said Dai, the Sam and Helen Worden Professor of Physics and Astronomy.
    The finding provides experimental proof for ideas that had only existed in theoretical models. It also shows how the intricate geometry of kagome lattices can be used as a design tool for controlling the behavior of electrons in solids.
    “By identifying active flat bands, we’ve demonstrated a direct connection between lattice geometry and emergent quantum states,” said Yi, an associate professor of physics and astronomy.
    The research team employed two advanced synchrotron techniques alongside theoretical modeling to investigate the presence of active standing-wave electron modes. They used angle-resolved photoemission spectroscopy (ARPES) to map electrons emitted under synchrotron light, revealing distinct signatures associated with compact molecular orbitals. Resonant inelastic X-ray scattering (RIXS) measured magnetic excitations linked to these electronic modes.

    “The ARPES and RIXS results of our collaborative team give a consistent picture that flat bands here are not passive spectators but active participants in shaping the magnetic and electronic landscape,” said Si, the Harry C. and Olga K. Wiess Professor of Physics and Astronomy, “This is amazing to see given that, until now, we were only able to see such features in abstract theoretical models.”
    Theoretical support was provided by analyzing the effect of strong correlations starting from a custom-built electronic lattice model, which replicated the observed features and guided the interpretation of results. Fang Xie, a Rice Academy Junior Fellow and co-first author, led that portion of the study.
    Obtaining such precise data required unusually large and pure crystals of CsCr₃Sb₅, synthesized using a refined method that produced samples 100 times larger than previous efforts, said Zehao Wang, a Rice graduate student and co-first author.
    The work underscores the potential of interdisciplinary research across fields of study, said Yucheng Guo, a Rice graduate student and co-first author who led the ARPES work.
    “This work was possible due to the collaboration that consisted of materials design, synthesis, electron and magnetic spectroscopy characterization and theory,” Guo said.
    Co-authors from Rice include Yuefei Huang, Bin Gao, Ji Seop Oh, Han Wu, Zheng Ren, Yuan Fang, Yiming Wang, Ananya Biswas, Yichen Zhang, Ziqin Yue, Boris Yakobson and Junichiro Kono.
    Other contributors include Hsiao-Yu Huang, Jun Okamoto, Ganesha Channagowdra, Atsushi Fujimori and Chien-Te Chen of Taiwan’s National Synchrotron Radiation Research Center; Xingye Lu of Beijing Normal University; Zhaoyu Liu and Jiun-Haw Chu of the University of Washington; Cheng Hu, Chris Jozwiak, Aaron Bostwick and Eli Rotenberg of the Lawrence Berkeley National Laboratory; Makoto Hashimoto and Donghui Lu of the SLAC National Accelerator Laboratory; Robert Birgeneau of the University of California, Berkeley; and Guang-Han Cao of Zhejiang University.
    The U.S. Department of Energy, Robert A. Welch Foundation, Gordon and Betty Moore Foundation, Air Force Office of Scientific Research, National Science Foundation and Vannevar Bush Faculty Fellowship program supported this study. More

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    River turbulence can push toxic pollutants into the air

    Toxic pollutants from a Southern California river are infiltrating the air.

    Polluted water surging along a turbulent section of the Tijuana River in San Diego can release toxic gases, including hydrogen sulfide, into the air, researchers report in the Aug. 28 Science. In a nearby neighborhood, hydrogen sulfide — produced from sewage breakdown and known for its rotten egg smell — peaked at levels thousands of times the typical urban amounts.

    “As far as we can tell, this is one of, if not the first time, that we’ve seen a full-on air pollution crisis caused by a river, especially one so close to the community,” says Benjamin Rico, an atmospheric chemist at the University of California, San Diego. More

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    20 years after Hurricane Katrina, is the U.S. better prepared? 

    In late August 2005, Hurricane Katrina devastated the U.S. Gulf Coast. The storm cut a deadly swath through Louisiana, Mississippi and Alabama, deluging coastal towns as surges of ocean water swept relentlessly ashore, driven by powerful winds. The sheer force of the surging waters overpowered levees meant to protect low-lying New Orleans from floodwaters; the levees failed, and about 80 percent of the city was inundated.

    In all, the hurricane caused more than 1,800 fatalities, displaced hundreds of thousands of people from their homes and was responsible for about $125 billion in property damage. It’s one of the two costliest Atlantic hurricanes on record, tied with 2017’s Hurricane Harvey. More