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    The human brain can be squished 10 times as easily as polystyrene foam

    Researchers used MRI scans and an algorithm to measure the stiffness and resilience to pressure of the brain in living people

    Humans

    14 December 2022

    By Karmela Padavic-Callaghan
    Brains are surprisingly squishyShutterstock/Teeradej
    Though they may look like they are made from rubber, human brains are softer and squishier. Their ability to resist pressure is much less than the polystyrene foam used for packaging, more comparable to that of Jell-O.
    Nicholas Bennion at Cardiff University in the UK and his colleagues set out to develop a method for obtaining more accurate measurements of the brain’s physical properties inside living humans. Most of what we know about how brain tissue reacts to instruments touching it during neurosurgery comes from organs that have been cut into or removed and preserved in chemicals, which can affect tissue stiffness and resilience.
    The researchers performed MRI scans of people lying face down and then face up to shift the location of the brain in the skull. By analysing this data with a machine learning algorithm, they were able to work out different material characteristics of the brain and tissues that connect it to the skull. They quantified how much the brain collapses when pressed on, how it reacts to being pushed sideways and how springy the connective tissues are.Advertisement
    “If you take a brain which hasn’t been preserved in any way, its stiffness is incredibly low, and it breaks apart very easily. And it really is probably a lot softer than most people realise,” says Bennion.
    The team found that brain matter can be compressed up to 10 times as easily as polystyrene foam and that its resilience to being pushed sideways is about a thousandth of what it would be if it were made from rubber – its squishiness is comparable to a slab of Jell-O. Bennion says that the algorithm calculated that the tissues connecting the brain to the skull were also fairly soft, possibly to protect the brain from moving too abruptly.
    Though researchers have long known that brains are very soft and very fragile, the new study makes that notion precise enough to better inform sensitive surgical procedures, says Ellen Kuhl at Stanford University in California.
    The new method, however, may not fully capture the way the brain deforms during motions more violent than shifting positions, such as head trauma in an contact sport or traffic accident, says Krystyn Van Vliet at the Massachusetts Institute of Technology. In these situations, the flow of fluids within the brain can change its material properties.
    The team hopes the model can now be used to predict brain shifts that would occur during surgery for each individual patient based on pre-operative MRI scans. This may eliminate the need for inserting and re-inserting instruments into the brain until they hit the correct spot, making procedures less invasive.
    Journal reference: Journal of the Royal Society Interface, DOI: 10.1098/rsif.2022.0557

    More on these topics: More

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    Plym to Pamlico review: Nuclear test veterans find poignant voice

    Would your radiation badge work? What would it be like to witness a nuclear bomb blast? The early uncertain days of the UK’s nuclear test programme are poignantly recalled by service veterans in a series of four films at the Plym to Pamlico exhibition

    Humans

    13 December 2022

    By Laura Cooke
    A screengrab from the British Nuclear Test Veterans Association nuclear test films, part of the Plym to Pamlico exhibition.British Nuclear Test Veterans Association
    Plym to Pamlico
    The Royal Engineers Museum, Gillingham, UK
    Until 12 March 2023
    From flying through mushroom clouds collecting radioactive samples to waking up in a tent covered in aggressive crustaceans, a new series of films is lifting the lid on what it was like to take part in the UK’s nuclear testing programme in the 1950s and 1960s.
    Four short films mix animation with images taken during operations from the … More

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    Porvenir massacre: Did US army have larger role in 1918 killings?

    By Kismat Shrees
    The first archaeological survey of the site of Porvenir, where a century-old massacre occurred at the US-Mexico border, has discovered bullets and cartridge casings for US military weapons.
    A ballistics analysis has raised new questions about the role of the US Army in the 1918 Porvenir massacre, where Texas Rangers killed 15 unarmed Mexican boys and men. The new evidence collected by David Keller, an archaeologist at Sul Ross State University in Texas, and colleagues suggest the US army could have played a bigger role in the massacre than previously thought.

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    Homo Sapiens Rediscovered review: Hunting human origin stories

    From a bone fragment of a mysterious new species to the latest on cave art, Paul Pettit’s powerful new book shows how science is rewriting the past

    Humans

    7 December 2022

    By Alison George
    Upper Palaeolithic art on a replica of the Chauvet cave, south-east FranceAndiA/Alamy
    Homo Sapiens Rediscovered
    Paul Pettitt (Thames & Hudson)
    WHO are we? This fundamental question has always exercised humanity. One way to approach it is to look at our origins and the evolutionary journey we have taken. Today, thanks to powerful new tools, we can look at the lives of our ancestors in unprecedented detail: the meals they ate, their relationships. And through their art and other practices, we can even get hints about their beliefs about the world.
    Paul Pettitt, … More

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    The science of self-knowledge is important, even if it is a bit fuzzy

    Who you really are is a major question worth pursuing for most people, so research into self-knowledge is important despite the fact it often relies on subjective findings

    Humans

    | Leader

    7 December 2022

    Eugenio Marongiu/Cultura Creative RF/Alamy
    WHO am I? It is a simple yet profound question, long considered worth grappling with on the basis that self-knowledge is good. Take personality, for instance. Intuitively at least, it makes sense to think that if you know your personality, you will make wiser life decisions, have better relationships and ultimately enjoy greater well-being.
    That may be true, but studying how accurately we perceive our personality, the subject of our cover story Self-knowledge: How to know your true personality and why it matters, is fraught with difficulties. The fact is there is no objective perspective on your personality in … More

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    Don’t Miss: The way of water, first of four sequels to Avatar

    Spotlight on plankton, the ocean’s fascinating, bite-sized creaturesEvery night, plankton take a journey to shallower waters to feed, prompting predators to follow in search of a very small, but tasty, snack. These images are taken from a new book, Planktonia, illuminating their daily ascent More

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    A bizarre gamma-ray burst breaks the rules for these cosmic eruptions

    Astronomers have spotted a bright gamma-ray burst that upends previous theories of how these energetic cosmic eruptions occur.

    For decades, astronomers thought that GRBs came in two flavors, long and short — that is, lasting longer than two seconds or winking out more quickly. Each type has been linked to different cosmic events. But about a year ago, two NASA space telescopes caught a short GRB in long GRB’s clothing: It lasted a long time but originated from a short GRB source.

    “We had this black-and-white vision of the universe,” says astrophysicist Eleonora Troja of the Tor Vergata University of Rome. “This is the red flag that tells us, nope, it’s not. Surprise!”

    This burst, called GRB 211211A, is the first that unambiguously breaks the binary, Troja and others report December 7 in five papers in Nature and Nature Astronomy.

    Prior to the discovery of this burst, astronomers mostly thought that there were just two ways to produce a GRB. The collapse of a massive star just before it explodes in a supernova could make a long gamma-ray burst, lasting more than two seconds (SN: 10/28/22). Or a pair of dense stellar corpses called neutron stars could collide, merge and form a new black hole, releasing a short gamma-ray burst of two seconds or less.

    But there had been some outliers. A surprisingly short GRB in 2020 seemed to come from a massive star’s implosion (SN: 8/2/21). And some long-duration GRBs dating back to 2006 lacked a supernova after the fact, raising questions about their origins.

    “We always knew there was an overlap,” says astrophysicist Chryssa Kouveliotou of George Washington University in Washington, D.C., who wrote the 1993 paper that introduced the two GRB categories, but was not involved in the new work. “There were some outliers which we did not know how to interpret.”

    There’s no such mystery about GRB 211211A: The burst lasted more than 50 seconds and was clearly accompanied by a kilonova, the characteristic glow of new elements being forged after a neutron star smashup.

    This shows the glow of a kilonova that followed the oddball gamma-ray burst called GRB 211211A, in images from the Gemini North telescope and the Hubble Space Telescope.M. Zamani/International Gemini Observatory/NOIRLab/NSF/AURA, NASA, ESA

    “Although we suspected it was possible that extended emission GRBs were mergers … this is the first confirmation,” says astrophysicist Benjamin Gompertz of the University of Birmingham in England, who describes observations of the burst in Nature Astronomy. “It has the kilonova, which is the smoking gun.”

    NASA’s Swift and Fermi space telescopes detected the explosion on December 11, 2021, in a galaxy about 1.1 billion light-years away. “We thought it was a run-of-the-mill long gamma-ray burst,” says astrophysicist Wen-fai Fong of Northwestern University in Evanston, Ill.

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    It was relatively close by, as GRBs go. So that allowed Fong’s and Troja’s research groups to independently continue closely observing the burst in great detail using telescopes on the ground, the teams report in Nature.

    As the weeks wore on and no supernova appeared, the researchers grew confused. Their observations revealed that whatever had made the GRB had also emitted much more optical and infrared light than is typical for the source of a long GRB.

    After ruling out other explanations, Troja and colleagues compared the burst’s aftereffects with the first kilonova ever observed in concert with ripples in spacetime called gravitational waves (SN: 10/16/17). The match was nearly perfect. “That’s when many people got convinced we were talking about a kilonova,” she says.

    In retrospect, it feels obvious that it was a kilonova, Troja says. But in the moment, it felt as impossible as seeing a lion in the Arctic. “It looks like a lion, it roars like a lion, but it shouldn’t be here, so it cannot be,” she says. “That’s exactly what we felt.”

    Now the question is, what happened? Typically, merging neutron stars collapse into a black hole almost immediately. The gamma rays come from material that is superheated as it falls into the black hole, but the material is scant, and the black hole gobbles it up within two seconds. So how did GRB 211211A keep its light going for almost a minute?

    It’s possible that the neutron stars first merged into a single, larger neutron star, which briefly resisted the pressure to collapse into a black hole. That has implications for the fundamental physics that describes how difficult it is to crush neutrons into a black hole, Gompertz says.

    Another possibility is that a neutron star collided with a small black hole, about five times the mass of the sun, instead of another neutron star. And the process of the black hole eating the neutron star took longer.

    Or it could have been something else entirely: a neutron star merging with a white dwarf, astrophysicist Bing Zhang of the University of Nevada, Las Vegas and colleagues suggest in Nature. “We suggest a third type of progenitor, something very different from the previous two types,” he says.

    White dwarfs are the remnants of smaller stars like the sun, and are not as dense or compact as neutron stars. A collision between a white dwarf and a neutron star could still produce a kilonova if the white dwarf is very heavy.

    The resulting object could be a highly magnetized neutron star called a magnetar (SN: 12/1/20). The magnetar could have continued pumping energy into gamma rays and other wavelengths of light, extending the life of the burst, Zhang says.

    Whatever its origins, GRB 211211A is a big deal for physics. “It is important because we wanted to understand, what on Earth are these events?” Kouveliotou says.

    Figuring out what caused it could illuminate how heavy elements in the universe form. And some previously seen long GRBs that scientists thought were from supernovas might actually be actually from mergers.

    To learn more, scientists need to find more of these binary-busting GRBs, plus observations of gravitational waves at the same time. Trejo thinks they’ll be able to get that when the Laser Interferometer Gravitational-Wave Observatory, or LIGO, comes back online in 2023.

    “I hope that LIGO will produce some evidence,” Kouveliotou says. “Nature might be graceful and give us a couple of these events with gravitational wave counterparts, and maybe [help us] understand what’s going on.” More

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    Self-knowledge: How to know your true personality and why it matters

    When it comes to knowing yourself, your own perception of your personality doesn’t necessarily align with that of people around you. But which is more accurate? And can discovering your true nature lead to a better life?

    Humans

    7 December 2022

    By Daniel Cossins
    Jason Ford
    EVER wondered what other people think of you – I mean, what they really think of you? I consider myself decent company, for instance, even if I know I get a bit vociferous after a few pints of bitter. I like to think I am open-minded and considerate, too, though I recognise I can be dismissive at times. But lately, particularly the morning after a few of those pints, I have become curious about how other people see me.
    Let’s be honest: sometimes I wonder if people think I’m more obnoxious than I realise. Because presumably you wouldn’t know. That is partly where the intrigue lies for me. How accurately do we see ourselves? And who is the real you anyway – the person you think you are, or the person other people see?
    It isn’t that I am self-obsessed, you understand. I am just intrigued about the extent to which the way people see my personality tallies with the way I view myself. Ultimately, I wonder whether being more aware of these shadowy hinterlands of self-knowledge might make life better – not only for me, but for those who spend time with me. Did I say I wasn’t self-obsessed?
    In search of answers, I did what most sensible people tend to avoid: I solicited honest insights into my nature from a dozen friends, family members and colleagues. I asked them to fill out a 60-point questionnaire designed by psychologists to assess personality, and to give the two traits they most associate with me – one positive and one negative. Then I waited nervously for the scales to fall from my eyes.
    Personality test … More