Computers Math

Engineers at Duke University have developed an electronics-free, entirely soft robot shaped like a dragonfly that can skim across water and react to environmental conditions such as pH, temperature or the presence of oil. The proof-of-principle demonstration could be the precursor to more advanced, autonomous, long-range environmental sentinels for monitoring a wide range of potential telltale signs of problems.
The soft robot is described online March 25 in the journal Advanced Intelligent Systems.
Soft robots are a growing trend in the industry due to their versatility. Soft parts can handle delicate objects such as biological tissues that metal or ceramic components would damage. Soft bodies can help robots float or squeeze into tight spaces where rigid frames would get stuck.
The expanding field was on the mind of Shyni Varghese, professor of biomedical engineering, mechanical engineering and materials science, and orthopaedic surgery at Duke, when inspiration struck.
“I got an email from Shyni from the airport saying she had an idea for a soft robot that uses a self-healing hydrogel that her group has invented in the past to react and move autonomously,” said Vardhman Kumar, a PhD student in Varghese’s laboratory and first author of the paper. “But that was the extent of the email, and I didn’t hear from her again for days. So the idea sort of sat in limbo for a little while until I had enough free time to pursue it, and Shyni said to go for it.”
In 2012, Varghese and her laboratory created a self-healing hydrogel that reacts to changes in pH in a matter of seconds. Whether it be a crack in the hydrogel or two adjoining pieces “painted” with it, a change in acidity causes the hydrogel to form new bonds, which are completely reversible when the pH returns to its original levels. More

The very first moments of the Universe can be reconstructed mathematically even though they cannot be observed directly. Physicists from the Universities of Göttingen and Auckland (New Zealand) have greatly improved the ability of complex computer simulations to describe this early epoch. They discovered that a complex network of structures can form in the first trillionth of a second after the Big Bang. The behaviour of these objects mimics the distribution of galaxies in today’s Universe. In contrast to today, however, these primordial structures are microscopically small. Typical clumps have masses of only a few grams and fit into volumes much smaller than present-day elementary particles. The results of the study have been published in the journal Physical Review D.
The researchers were able to observe the development of regions of higher density that are held together by their own gravity. “The physical space represented by our simulation would fit into a single proton a million times over,” says Professor Jens Niemeyer, head of the Astrophysical Cosmology Group at the University of Göttingen. “It is probably the largest simulation of the smallest area of the Universe that has been carried out so far.” These simulations make it possible to calculate more precise predictions for the properties of these vestiges from the very beginnings of the Universe.
Although the computer-simulated structures would be very short-lived and eventually “vaporise” into standard elementary particles, traces of this extreme early phase may be detectable in future experiments. “The formation of such structures, as well as their movements and interactions, must have generated a background noise of gravitational waves,” says Benedikt Eggemeier, a PhD student in Niemeyer’s group and first author of the study. “With the help of our simulations, we can calculate the strength of this gravitational wave signal, which might be measurable in the future.”
It is also conceivable that tiny black holes could form if these structures undergo runaway collapse. If this happens they could have observable consequences today, or form part of the mysterious dark matter in the Universe. “On the other hand,” says Professor Easther, “If the simulations predict black holes form, and we don’t see them, then we will have found a new way to test models of the infant Universe.”
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Materials provided by University of Göttingen. Note: Content may be edited for style and length. More

Microswimmers are artificial, self-propelled, microscopic particles. They are capable of directional motion in a solution. The Molecular Nanophotonics Group at Leipzig University has developed special particles that are smaller than one-thirtieth of the diameter of a hair. They can change their direction of motion by heating tiny gold particles on their surface and converting this energy into motion. “However, these miniaturised machines cannot take in and learn information like their living counterparts. To achieve this, we control the microswimmers externally so that they learn to navigate in a virtual environment through what is known as reinforcement learning,” said Cichos.
With the help of virtual rewards, the microswimmers find their way through the liquid while repeatedly being thrown off of their path, mainly by Brownian motion. “Our results show that the best swimmer is not the one that is fastest, but rather that there is an optimal speed,” said Viktor Holubec, who worked on the project as a fellow of the Alexander von Humboldt Foundation and has now returned to the university in Prague.
According to the scientists, linking artificial intelligence and active systems like in these microswimmers is a first small step towards new intelligent microscopic materials that can autonomously perform tasks while also adapting to their new environment. At the same time, they hope that the combination of artificial microswimmers and machine learning methods will provide new insights into the emergence of collective behaviour in biological systems. “Our goal is to develop artificial, smart building blocks that can perceive their environmental influences and actively react to them,” said the physicist. Once this method is fully developed and has been applied to other material systems, including biological ones, it could be used, for example, in the development of smart drugs or microscopic robot swarms.
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Materials provided by Universität Leipzig. Original written by Susann Husters. Note: Content may be edited for style and length. More

The secret to building superconducting quantum computers with massive processing power may be an ordinary telecommunications technology — optical fiber.
Physicists at the National Institute of Standards and Technology (NIST) have measured and controlled a superconducting quantum bit (qubit) using light-conducting fiber instead of metal electrical wires, paving the way to packing a million qubits into a quantum computer rather than just a few thousand. The demonstration is described in the March 25 issue of Nature.
Superconducting circuits are a leading technology for making quantum computers because they are reliable and easily mass produced. But these circuits must operate at cryogenic temperatures, and schemes for wiring them to room-temperature electronics are complex and prone to overheating the qubits. A universal quantum computer, capable of solving any type of problem, is expected to need about 1 million qubits. Conventional cryostats — supercold dilution refrigerators — with metal wiring can only support thousands at the most.
Optical fiber, the backbone of telecommunications networks, has a glass or plastic core that can carry a high volume of light signals without conducting heat. But superconducting quantum computers use microwave pulses to store and process information. So the light needs to be converted precisely to microwaves.
To solve this problem, NIST researchers combined the fiber with a few other standard components that convert, convey and measure light at the level of single particles, or photons, which could then be easily converted into microwaves. The system worked as well as metal wiring and maintained the qubit’s fragile quantum states.
“I think this advance will have high impact because it combines two totally different technologies, photonics and superconducting qubits, to solve a very important problem,” NIST physicist John Teufel said. “Optical fiber can also carry far more data in a much smaller volume than conventional cable.”
Normally, researchers generate microwave pulses at room temperature and then deliver them through coaxial metal cables to ¬¬cryogenically maintained superconducting qubits. The new NIST setup used an optical fiber instead of metal to guide light signals to cryogenic photodetectors that converted signals back to microwaves and delivered them to the qubit. For experimental comparison purposes, microwaves could be routed to the qubit through either the photonic link or a regular coaxial line. More

The heart of any computer, its central processing unit, is built using semiconductor technology, which is capable of putting billions of transistors onto a single chip. Now, researchers from the group of Menno Veldhorst at QuTech, a collaboration between TU Delft and TNO, have shown that this technology can be used to build a two-dimensional array of qubits to function as a quantum processor. Their work, a crucial milestone for scalable quantum technology, was published today in Nature.
Quantum computers have the potential to solve problems that are impossible to address with classical computers. Whereas current quantum devices hold tens of qubits — the basic building block of quantum technology — a future universal quantum computer capable of running any quantum algorithm will likely consist of millions to billions of qubits. Quantum dot qubits hold the promise to be a scalable approach as they can be defined using standard semiconductor manufacturing techniques. Veldhorst: ‘By putting four such qubits in a two-by-two grid, demonstrating universal control over all qubits, and operating a quantum circuit that entangles all qubits, we have made an important step forward in realizing a scalable approach for quantum computation.’
An entire quantum processor
Electrons trapped in quantum dots, semiconductor structures of only a few tens of nanometres in size, have been studied for more than two decades as a platform for quantum information. Despite all promises, scaling beyond two-qubit logic has remained elusive. To break this barrier, the groups of Menno Veldhorst and Giordano Scappucci decided to take an entirely different approach and started to work with holes (i.e. missing electrons) in germanium. Using this approach, the same electrodes needed to define the qubits could also be used to control and entangle them. ‘No large additional structures have to be added next to each qubit such that our qubits are almost identical to the transistors in a computer chip,’ says Nico Hendrickx, graduate student in the group of Menno Veldhorst and first author of the article. ‘Furthermore, we have obtained excellent control and can couple qubits at will, allowing us to program one, two, three, and four-qubit gates, promising highly compact quantum circuits.’
2D is key
After successfully creating the first germanium quantum dot qubit in 2019, the number of qubits on their chips has doubled every year. ‘Four qubits by no means makes a universal quantum computer, of course,’ Veldhorst says. ‘But by putting the qubits in a two-by-two grid we now know how to control and couple qubits along different directions.’ Any realistic architecture for integrating large numbers of qubits requires them to be interconnected along two dimensions.
Germanium as a highly versatile platform
Demonstrating four-qubit logic in germanium defines the state-of-the-art for the field of quantum dots and marks an important step toward dense, and extended, two-dimensional semiconductor qubit grids. Next to its compatibility with advanced semiconductor manufacturing, germanium is also a highly versatile material. It has exciting physics properties such as spin-orbit coupling and it can make contact to materials like superconductors. Germanium is therefore considered as an excellent platform in several quantum technologies. Veldhorst: ‘Now that we know how to manufacture germanium and operate an array of qubits, the germanium quantum information route can truly begin.’
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Materials provided by Delft University of Technology. Note: Content may be edited for style and length. More

Materials science likes to take nature and the special properties of living beings that could potentially be transferred to materials as a model. A research team led by chemist Professor Andreas Walther of Johannes Gutenberg University Mainz (JGU) has succeeded in endowing materials with a bioinspired property: Wafer-thin stiff nanopaper instantly becomes soft and elastic at the push of a button. “We have equipped the material with a mechanism so that the strength and stiffness can be modulated via an electrical switch,” explained Walther. As soon as an electric current is applied, the nanopaper becomes soft; when the current flow stops, it regains its strength. From an application perspective, this switchability could be interesting for damping materials, for example. The work, which also involved scientists from the University of Freiburg and the Cluster of Excellence on “Living, Adaptive, and Energy-autonomous Materials Systems” (livMatS) funded by the German Research Foundation (DFG), was published in Nature Communications.
Inspiration from the seafloor: Mechanical switch serves a protective function
The nature-based inspiration in this case comes from sea cucumbers. These marine creatures have a special defense mechanism: When they are attacked by predators in their habitat on the seafloor, sea cucumbers can adapt and strengthen their tissue so that their soft exterior immediately stiffens. “This is an adaptive mechanical behavior that is fundamentally difficult to replicate,” said Professor Andreas Walther. With their work now published, his team has succeeded in mimicking the basic principle in a modified form using an attractive material and an equally attractive switching mechanism.
The scientists used cellulose nanofibrils extracted and processed from the cell wall of trees. Nanofibrils are even finer than the microfibers in standard paper and result in a completely transparent, almost glass-like paper. The material is stiff and strong, appealing for lightweight construction. Its characteristics are even comparable to those of aluminum alloys. In their work, the research team applied electricity to these cellulose nanofibril-based nanopapers. By means of specially designed molecular changes, the material becomes flexible as a result. The process is reversible and can be controlled by an on/off switch.
“This is extraordinary. All the materials around us are not very changeable, they do not easily switch from stiff to elastic and vice versa. Here, with the help of electricity, we can do that in a simple and elegant way,” said Walther. The development is thus moving away from classic static materials toward materials with properties that can be adaptively adjusted. This is relevant for mechanical materials, which can thus be made more resistant to fracture, or for adaptive damping materials, which could switch from stiff to compliant when overloaded, for example.
Targeting a material with its own energy storage for autonomous on/off switching
At the molecular level, the process involves heating the material by applying a current and thus reversibly breaking cross-linking points. The material softens in correlation with the applied voltage, i.e., the higher the voltage, the more cross-linking points are broken and the softer the material becomes. Professor Andreas Walther’s vision for the future also starts at the point of power supply: While currently a power source is needed to start the reaction, the next goal would be to produce a material with its own energy storage system, so that the reaction is essentially triggered “internally” as soon as, for example, an overload occurs and damping becomes necessary. “Now we still have to flip the switch ourselves, but our dream would be for the material system to be able to accomplish this on its own.”
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Materials provided by Johannes Gutenberg Universitaet Mainz. Note: Content may be edited for style and length. More

Have you ever wondered why you are able to hear a sentence and understand its meaning — given that the same words in a different order would have an entirely different meaning? New research involving neuroimaging and A.I., describes the complex network within the brain that comprehends the meaning of a spoken sentence.
“It has been unclear whether the integration of this meaning is represented in a particular site in the brain, such as the anterior temporal lobes, or reflects a more network level operation that engages multiple brain regions,” said Andrew Anderson, Ph.D., research assistant professor in the University of Rochester Del Monte Institute for Neuroscience and lead author on of the study which was published in the Journal of Neuroscience. “The meaning of a sentence is more than the sum of its parts. Take a very simple example — ‘the car ran over the cat’ and ‘the cat ran over the car’ — each sentence has exactly the same words, but those words have a totally different meaning when reordered.”
The study is an example of how the application of artificial neural networks, or A.I., are enabling researchers to unlock the extremely complex signaling in the brain that underlies functions such as processing language. The researchers gather brain activity data from study participants who read sentences while undergoing fMRI. These scans showed activity in the brain spanning across a network of different regions — anterior and posterior temporal lobes, inferior parietal cortex, and inferior frontal cortex. Using the computational model InferSent — an A.I. model developed by Facebook trained to produce unified semantic representations of sentences — the researchers were able to predict patterns of fMRI activity reflecting the encoding of sentence meaning across those brain regions.
“It’s the first time that we’ve applied this model to predict brain activity within these regions, and that provides new evidence that contextualized semantic representations are encoded throughout a distributed language network, rather than at a single site in the brain.”
Anderson and his team believe the findings could be helpful in understanding clinical conditions. “We’re deploying similar methods to try to understand how language comprehension breaks down in early Alzheimer’s disease. We are also interested in moving the models forward to predict brain activity elicited as language is produced. The current study had people read sentences, in the future we’re interested in moving forward to predict brain activity as people might speak sentences.”
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Materials provided by University of Rochester Medical Center. Original written by Kelsie Smith Hayduk. Note: Content may be edited for style and length. More

All viruses mutate as they make copies of themselves to spread and thrive. SARS-CoV-2, the virus the causes COVID-19, is proving to be no different. There are currently more than 4,000 variants of COVID-19, which has already killed more than 2.7 million people worldwide during the pandemic.
The UK variant, also known as B.1.1.7, was first detected in September 2020, and is now causing 98 percent of all COVID-19 cases in the United Kingdom. And it appears to be gaining a firm grip in about 100 other countries it has spread to in the past several months, including France, Denmark, and the United States.
The World Health Organization says B.1.1.7 is one of several variants of concern along with others that have emerged in South Africa and Brazil.
“The UK, South Africa, and Brazil variants are more contagious and escape immunity easier than the original virus,” said Victor Padilla-Sanchez, a research scientist at The Catholic University of America. “We need to understand why they are more infectious and, in many cases, more deadly.”
All three variants have undergone changes to their spike protein — the part of the virus which attaches to human cells. As a result, they are better at infecting cells and spreading.
In a research paper published in January 2021 in Research Ideas and Outcomes, Padilla-Sanchez discusses the UK and South African variants in detail. He presents a computational analysis of the structure of the spike glycoprotein bound to the ACE2 receptor where the mutations have been introduced. His paper outlines the reason why these variants bind better to human cells. More