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    New model connects respiratory droplet physics with spread of Covid-19

    Respiratory droplets from a cough or sneeze travel farther and last longer in humid, cold climates than in hot, dry ones, according to a study on droplet physics by an international team of engineers. The researchers incorporated this understanding of the impact of environmental factors on droplet spread into a new mathematical model that can be used to predict the early spread of respiratory viruses including COVID-19, and the role of respiratory droplets in that spread.
    The team developed this new model to better understand the role that droplet clouds play in the spread of respiratory viruses. Their model is the first to be based on a fundamental approach taken to study chemical reactions called collision rate theory, which looks at the interaction and collision rates of a droplet cloud exhaled by an infected person with healthy people. Their work connects population-scale human interaction with their micro-scale droplet physics results on how far and fast droplets spread, and how long they last.
    Their results were published June 30 in the journal Physics of Fluids.
    “The basic fundamental form of a chemical reaction is two molecules are colliding. How frequently they’re colliding will give you how fast the reaction progresses,” said Abhishek Saha, a professor of mechanical engineering at the University of California San Diego, and one of the authors of the paper. “It’s exactly the same here; how frequently healthy people are coming in contact with an infected droplet cloud can be a measure of how fast the disease can spread.”
    They found that, depending on weather conditions, some respiratory droplets travel between 8 feet and 13 feet away from their source before evaporating, without even accounting for wind. This means that without masks, six feet of social distance may not be enough to keep one person’s exhalated particles from reaching someone else.
    “Droplet physics are significantly dependent on weather,” said Saha. “If you’re in a colder, humid climate, droplets from a sneeze or cough are going to last longer and spread farther than if you’re in a hot dry climate, where they’ll get evaporated faster. We incorporated these parameters into our model of infection spread; they aren’t included in existing models as far as we can tell.”
    The researchers hope that their more detailed model for rate of infection spread and droplet spread will help inform public health policies at a more local level, and can be used in the future to better understand the role of environmental factors in virus spread.

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    They found that at 35C (95F) and 40 percent relative humidity, a droplet can travel about 8 feet. However, at 5C (41F) and 80 percent humidity, a droplet can travel up to 12 feet. The team also found that droplets in the range of 14-48 microns possess higher risk as they take longer to evaporate and travel greater distances. Smaller droplets, on the other hand, evaporate within a fraction of a second, while droplets larger than 100 microns quickly settle to the ground due to weight.
    This is further evidence of the importance of wearing masks, which would trap particles in this critical range.
    The team of engineers from the UC San Diego Jacobs School of Engineering, University of Toronto and Indian Institute of Science are all experts in the aerodynamics and physics of droplets for applications including propulsion systems, combustion or thermal sprays. They turned their attention and expertise to droplets released when people sneeze, cough or talk when it became clear that COVID-19 is spread through these respiratory droplets. They applied existing models for chemical reactions and physics principles to droplets of a salt water solution — saliva is high in sodium chloride — which they studied in an ultrasonic levitator to determine the size, spread, and lifespan of these particles in various environmental conditions.
    Many current pandemic models use fitting parameters to be able to apply the data to an entire population. The new model aims to change that.
    “Our model is completely based on “first principles” by connecting physical laws that are well understood, so there is next to no fitting involved,” said Swetaprovo Chaudhuri, professor at University of Toronto and a co-author. “Of course, we make idealized assumptions, and there are variabilities in some parameters, but as we improve each of the submodels with specific experiments and including the present best practices in epidemiology, maybe a first principles pandemic model with high predictive capability could be possible.”
    There are limitations to this new model, but the team is already working to increase the model’s versatility.
    “Our next step is to relax a few simplifications and to generalize the model by including different modes of transmission,” said Saptarshi Basu, professor at the Indian Institute of Science and a co-author. “A set of experiments are also underway to investigate the respiratory droplets that settle on commonly touched surfaces.” More

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    Quantum exciton found in magnetic van der Waals material NiPS3

    Things can always be done faster, but can anything beat light? Computing with light instead of electricity is seen as a breakthrough to boost the computer speeds. Transistors, the building blocks of data circuits, require to switch electrical signals into light in order to transmit the information via a fiber-optic cable. Optical computing could potentially save the time and energy used to be spent for such conversion. In addition to the high-speed transmission, outstanding low-noise properties of photons make them ideal for exploring quantum mechanics. At the heart of such compelling applications is to secure a stable light source, especially in a quantum state.
    When light is shone onto electrons in a semiconductor crystal, a conduction electron can combine with a positively charged hole in the semiconductor to create a bound state, the so-called exciton. Flowing like electrons but emitting light when the electron-hole pair gets back together, excitons could speed up the overall data transmission circuits. In addition, plenty of exotic physical phases like superconductivity are speculated as phenomena arising from excitons. Despite the richness of exotic theoretical predictions and its long history (first reported in the 1930’s), much of the physics regarding excitons has been mostly about its initial concept of “simple” binding of an electron and a hole, rarely updated from the findings in the 1930s.
    In the latest issue of the journal Nature, a research team led by Professor PARK Je-Geun of the Department of Physics and Astronomy, Seoul National University — previously Associate Director of the Center for Correlated Electron Systems within the Institute for Basic Science (IBS, South Korea) — found a new type of exciton in magnetic van der Waals material NiPS3. “To host such a novel state of an exciton physics, it requires a direct bandgap and most importantly, magnetic order with strong quantum correlation. Notably, this study makes it the latter possible with NiPS3, a magnetic van der Waals material, an intrinsically correlated system,” notes Professor PARK Je-Geun, corresponding author of the study. Prof. Park’s group reported the first realization of exact 2D magnetic van der Waals materials using NiPS3 in 2016. Using the same material, they have demonstrated that NiPS3 hosts a completely different magnetic exciton state from the more conventional excitons known to date. This exciton state is intrinsically of many-body origin, which is an actual realization of a genuine quantum state. As such, this new work signals a significant shift in the vibrant field of research in its 80 years of history.
    All of this unusual exciton physics in NiPS3 began with bizarrely high peaks spotted in early PL (photoluminescence) experiments done in 2016 by Prof. CHEONG Hyeonsik of Sogang University. It was soon followed by another optical absorption experiment done by Prof. KIM Jae Hoon of Yonsei University. Both sets of optical data clearly indicated two points of significant importance: one is the temperature dependence and the other extremely narrow resonant nature of the exciton.
    To understand the unusual findings, Prof. Park used a resonant inelastic X-ray scattering technique, known as RIXS, together with Dr. Ke-Jin Zhou at the Diamond Facilities, the UK. This new experiment was critical to the success of the overall project. First, it confirmed the existence of the 1.5 eV exciton peak beyond any doubt. Secondly, it provided an inspiring guide on how we could come up with a theoretical model and the ensuing calculations. This connection between the experiment and the theory played a pivotal role for them to crack the big puzzle in NiPS3.
    Using the analytical process shown above, Dr. KIM Beom Hyun and Prof. SON Young-Woo of the Korea Institute for Advanced Study carried out massive theoretical many-body calculations. By exploring massive quantum states totaling 1,500,000 in the Hilbert space, they concluded that all the experimental results could be consistent with a particular set of parameters. When they compared the theoretical results with the RIXS data (Fig. 3-a), it was clear that they came to a full understanding of the very unusual exciton phase of NiPS3. At last, the team could theoretically understand the magnetic exciton state of many-body nature, i.e., a genuine quantum exciton state.
    There are several vital distinctions to be made about the quantum magnetic exciton discovered in NiPS3 as compared with the more conventional exciton found in other 2D materials and all the other insulators having an exciton state. First and foremost, the excitons found in NiPS3 is intrinsically a quantum state arising from a transition from a Zhang-Rice triplet to a Zhang-Rice singlet. Second, it is almost a resolution-limited state, indicative of some kind of coherence present among the states. For comparison, all the other exciton states reported before are from extended Bloch states.
    It is probably too early for us to make any definite predictions; it might as well bring on the future of the related field of magnetic van der Waals researches, not to mention our lives. However, it is clear even at this moment that “The quantum nature of the new exciton state is unique and will attract a lot of attention for its potentials in the field of quantum information and quantum computing, to name only a few. Our work opens an interesting possibility of many magnetic van der Waals materials having similar quantum exciton states,” explains Professor Park.

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    Which way to the fridge? Common sense helps robots navigate

    A robot travelling from point A to point B is more efficient if it understands that point A is the living room couch and point B is a refrigerator, even if it’s in an unfamiliar place. That’s the common sense idea behind a “semantic” navigation system developed by Carnegie Mellon University and Facebook AI Research (FAIR).
    That navigation system, called SemExp, last month won the Habitat ObjectNav Challenge during the virtual Computer Vision and Pattern Recognition conference, edging a team from Samsung Research China. It was the second consecutive first-place finish for the CMU team in the annual challenge.
    SemExp, or Goal-Oriented Semantic Exploration, uses machine learning to train a robot to recognize objects — knowing the difference between a kitchen table and an end table, for instance — and to understand where in a home such objects are likely to be found. This enables the system to think strategically about how to search for something, said Devendra S. Chaplot, a Ph.D. student in CMU’s Machine Learning Department.
    “Common sense says that if you’re looking for a refrigerator, you’d better go to the kitchen,” Chaplot said. Classical robotic navigation systems, by contrast, explore a space by building a map showing obstacles. The robot eventually gets to where it needs to go, but the route can be circuitous.
    Previous attempts to use machine learning to train semantic navigation systems have been hampered because they tend to memorize objects and their locations in specific environments. Not only are these environments complex, but the system often has difficulty generalizing what it has learned to different environments.
    Chaplot — working with FAIR’s Dhiraj Gandhi, along with Abhinav Gupta, associate professor in the Robotics Institute, and Ruslan Salakhutdinov, professor in the Machine Learning Department — sidestepped that problem by making SemExp a modular system.
    The system uses its semantic insights to determine the best places to look for a specific object, Chaplot said. “Once you decide where to go, you can just use classical planning to get you there.”
    This modular approach turns out to be efficient in several ways. The learning process can concentrate on relationships between objects and room layouts, rather than also learning route planning. The semantic reasoning determines the most efficient search strategy. Finally, classical navigation planning gets the robot where it needs to go as quickly as possible.
    Semantic navigation ultimately will make it easier for people to interact with robots, enabling them to simply tell the robot to fetch an item in a particular place, or give it directions such as “go to the second door on the left.”
    Video: https://www.youtube.com/watch?v=FhIut4bqFyw&feature=emb_logo

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    Atomtronic device could probe boundary between quantum, everyday worlds

    A new device that relies on flowing clouds of ultracold atoms promises potential tests of the intersection between the weirdness of the quantum world and the familiarity of the macroscopic world we experience every day. The atomtronic Superconducting QUantum Interference Device (SQUID) is also potentially useful for ultrasensitive rotation measurements and as a component in quantum computers.
    “In a conventional SQUID, the quantum interference in electron currents can be used to make one of the most sensitive magnetic field detectors,” said Changhyun Ryu, a physicist with the Material Physics and Applications Quantum group at Los Alamos National Laboratory. “We use neutral atoms rather than charged electrons. Instead of responding to magnetic fields, the atomtronic version of a SQUID is sensitive to mechanical rotation.”
    Although small, at only about ten millionths of a meter across, the atomtronic SQUID is thousands of times larger than the molecules and atoms that are typically governed by the laws of quantum mechanics. The relatively large scale of the device lets it test theories of macroscopic realism, which could help explain how the world we are familiar with is compatible with the quantum weirdness that rules the universe on very small scales. On a more pragmatic level, atomtronic SQUIDs could offer highly sensitive rotation sensors or perform calculations as part of quantum computers.
    The researchers created the device by trapping cold atoms in a sheet of laser light. A second laser intersecting the sheet “painted” patterns that guided the atoms into two semicircles separated by small gaps known as Josephson Junctions.
    When the SQUID is rotated and the Josephson Junctions are moved toward each other, the populations of atoms in the semicircles change as a result of quantum mechanical interference of currents through Josephson Junctions. By counting the atoms in each section of the semicircle, the researchers can very precisely determine the rate the system is rotating.
    As the first prototype atomtronic SQUID, the device has a long way to go before it can lead to new guidance systems or insights into the connection between the quantum and classical worlds. The researchers expect that scaling the device up to produce larger diameter atomtronic SQUIDs could open the door to practical applications and new quantum mechanical insights.

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    Predicting your personality from your smartphone data

    Everyone who uses a smartphone unavoidably generates masses of digital data that are accessible to others, and these data provide clues to the user’s personality. Psychologists at Ludwig-Maximilians-Universitaet in Munich (LMU) are studying how revealing these clues are.
    For most people around the world, smartphones have become an integral and indispensable component of their daily lives. The digital data that these devices incessantly collect are a veritable goldmine — not only for the five largest American IT companies, who make use of them for advertising purposes. They are also of considerable interest in other contexts. For instance, computational social scientists utilize smartphone data in order to learn more about personality traits and social behavior. In a study that appears in the journal PNAS, a team of researchers led by LMU psychologist Markus Bühner set out to determine whether conventional data passively collected by smartphones (such as times or frequencies of use) provide insights into users’ personalities. The answer was clear cut. “Yes, automated analysis of these data does allow us to draw conclusions about the personalities of users, at least for most of the major dimensions of personality,” says Clemens Stachl, who used to work with Markus Bühner (Chair of Psychological Methodologies and Diagnostics at LMU) and is now a researcher at Stanford University in California.
    The LMU team recruited 624 volunteers for their PhoneStudy project. The participants agreed to fill out an extensive questionnaire describing their personality traits, and to install an app that had been developed specially for the study on their phones for 30 days. The app was designed to collect coded information relating to the behavior of the user. The researchers were primarily interested in data pertaining to communication patterns, social behavior and mobility, together with users’ choice and consumption of music, the selection of apps used, and the temporal distribution of their phone usage over the course of the day. All the data on personality and smartphone use were then analyzed with the aid of machine-learning algorithms, which were trained to recognize and extract patterns from the behavioral data, and relate these patterns to the information obtained from the personality surveys. The ability of the algorithms to predict the personality traits of the users was then cross-validated on the basis of a new dataset. “By far the most difficult part of the project was the pre-processing of the huge amount of data collected and the training of the predictive algorithms,” says Stachl. “In fact, in order to perform the necessary calculations, we had to resort to the cluster of high-performance computers at the Leibniz Supercomputing Centre in Garching (LRZ).”
    The researchers focused on the five most significant personality dimensions (the Big Five) identified by psychologists, which enable them to characterize personality differences between individuals in a comprehensive way. These dimensions relate to the self-assessed contribution of each of the following traits to a given individual’s personality: (1) openness (willingness to adopt new ideas, experiences and values), (2) conscientiousness (dependability, punctuality, ambitiousness and discipline), (3) extraversion (sociability, assertiveness, adventurousness, dynamism and friendliness), (4) agreeableness (willingness to trust others, good natured, outgoing, obliging, helpful) and (5) emotional stability (self-confidence, equanimity, positivity, self-control). The automated analysis revealed that the algorithm was indeed able to successfully derive most of these personality traits from combinations of the multifarious elements of their smartphone usage. Moreover, the results provide hints as to which types of digital behavior are most informative for specific self-assessments of personality. For example, data pertaining to communication patterns and social behavior (as reflected by smartphone use) correlated strongly with levels of self-reported extraversion, while information relating to patterns of day and night-time activity was significantly predictive of self-reported degrees of conscientiousness. Notably, links with the category ‘openness’ only became apparent when highly disparate types of data (e.g., app usage) were combined.
    The results of the study are of great value to researchers, as studies have so far been almost exclusively based on self-assessments. The conventional method has proven to be sufficiently reliable in predicting levels of professional success, for instance. “Nevertheless, we still know very little about how people actually behave in their everyday lives — apart from what they choose to tell us on our questionnaires,” says Markus Bühner. “Thanks to their broad distribution, their intensive use and their very high level of performance, smartphones are an ideal tool with which to probe the relationships between self-reported and real patterns of behavior.
    Clemens Stachl is aware that his research might further stimulate the appetites of the dominant IT firms for data. In addition to regulating the use of passively collected data and strengthening rights to privacy, we also need to take a comprehensive look at the field of artificial intelligence, he says. “The user, not the machine, must be the primary focus of research in this area. It would be a serious mistake to adopt machine-based methods of learning without serious consideration of their wider implications.” The potential of these applications — in both research and business — is tremendous. “The opportunities opened up by today’s data-driven society will undoubtedly improve the lives of large numbers of people,” Stachl says. “But we must ensure that all sections of the population share the benefits offered by digital technologies.” More

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    New technology speeds up organic data transfer

    Researches are pushing the boundaries of data speed with a brand new type of organic LEDs.
    An international research team, involving Newcastle University experts, developed visible light communication (VLC) setup capable of a data rate of 2.2 Mb/s by employing a new type of organic light-emitting diodes (OLEDs).
    To reach this speed, the scientists created new far-red/near-infrared, solution-processed OLEDs. And by extending the spectral range to 700-1000nm, they successfully expanded the bandwidth and achieved the fastest-ever data speed for solution-based OLEDs.
    Described in the journal Light Science & Applications, the new OLEDs create opportunities for new internet-of-things (IoT) connectivity, as well as wearable and implantable biosensors technology.
    The project is a collaboration between Newcastle University, University College London, the London Centre for Nanotechnology, the Institute of Organic Chemistry — Polish Academy of Sciences (Warsaw, Poland) and the Institute for the Study of Nanostructured Materials — Research National Council (CNR-ISMN, Bologna, Italy).
    Dr Paul Haigh, Lecturer in Communications at Newcastle University’s Intelligent Sensing and Communications Group, was part of the research team. He led the development of a real-time transmission of signals that transmit as quickly as possible. He achieved this by using information modulation formats developed in-house, achieving approximately 2.2 Mb/s.
    Dr Haigh said: “Our team developed highly efficient long wavelength (far red/near-infrared) polymer LEDs for the first time, free of heavy metals which has been a long standing research challenge in the organic optoelectronics community. Achieving such high data rates opens up opportunities for the integration of portable, wearable or implantable organic biosensors into visible/ nearly (in)visible light communication links.”
    The demand for faster data transmission speeds is driving the popularity of light-emitting devices in VLC systems. LEDs have multiple applications and are used lighting systems, mobile phones and TV displays. While OLEDs don’t offer the same speed as inorganic LEDs and laser diodes do, they are cheaper to produce, recyclable and more sustainable.
    The data rate the team achieved through the pioneering device is high enough to support an indoor point-to-point link, with a view of IoT applications.
    The researchers highlight the possibility of achieving such data rates without computationally complex and power-demanding equalisers. Together with the absence of toxic heavy metals in the active layer of the OLEDs, the new VLC setup is promising for the integration of portable, wearable or implantable organic biosensors.

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    Will telehealth services become the norm following COVID-19 pandemic?

    The onset of the COVID-19 pandemic has broadly affected how health care is provided in the United States. One notable change is the expanded use of telehealth services, which have been quickly adopted by many health care providers and payers, including Medicare, to ensure patients’ access to care while reducing their risk of exposure to the coronavirus.
    In an article published in JAMA Oncology, Trevor Royce, MD, MS, MPH, an assistant professor of radiation oncology at the University of North Carolina Lineberger Comprehensive Cancer Center and UNC School of Medicine, said the routine use of telehealth for patients with cancer could have long-lasting and unforeseen effects on the provision and quality of care.
    “The COVID-19 pandemic has resulted in the rapid deregulation of telehealth services. This was done in part by lifting geographical restrictions, broadening patient, health care professional, and services eligibility,” said Royce, the article’s corresponding author. “It is likely aspects of telehealth continue to be part of the health care delivery system, beyond the pandemic.”
    The article’s other authors are UNC Lineberger’s Hanna K. Sanoff, MD, MPH, clinical medical director of the North Carolina Cancer Hospital and associate professor in the UNC School of Medicine Division of Hematology, and Amar Rewari, MD, MBA, from the Associates in Radiation Medicine, Adventist HealthCare Radiation Oncology Center in Rockville, Maryland.
    Royce said the widespread shift to telehealth was made possible, in part, by three federal economic stimulus packages and the Centers for Medicare and Medicaid Services making several policy changes in March that expanded Medicare recipients’ access to telehealth services.
    The policy changes included allowing telehealth services to be provided in a patient’s home. Medicare previously only paid for telehealth services in a facility in nonurban areas or areas with a health professional shortage. Medicare also approved payment for new patient appointments, expanded telehealth coverage to include 80 additional services, allowed for services to be carried out on a wider assortment of telecommunication systems — including remote video communications platforms, such as Zoom — and modified the restrictions of who can provide and supervise care.
    While the potential benefits of telehealth have been demonstrated during the pandemic, Royce said they must be balanced with concerns about care quality and safety.
    “There is a lot we don’t know about telehealth, and how its rapid adoption will impact our patients,” Royce said. “How will the safety and quality of care be impacted? How will we integrate essential components of the traditional doctor visit, including physical exam, lab work, scans and imaging? Will patients and doctors be more or less satisfied with their care? These are all potential downsides if we are not thoughtful with our adoption.”
    He said appropriate oversight of care is critical. There will be a continued need for objective patient assessments, such as patient-reported outcomes, physical examinations and laboratory tests, and to measure care quality and monitor for fraud. There are also a number of standard measures of care quality that can be implemented during the transition to telehealth, including tracking emergency room visits, hospitalizations and adverse events.
    Telehealth presents other challenges, as well. Though technology and internet access are now more widely available, they are not universally accessible. Where one lives, their socioeconomic status and comfort level with technology can be barriers to using telehealth services. A reliance on telehealth might lower participation in clinical trials, which can require regular in-person appointments.
    “Telehealth can be used to improve access to care in traditionally hard-to-reach populations. However, it is important to acknowledge that if we are not thoughtful in its adoption, the opposite could be true,” Royce said. “For example, will lower socioeconomic groups have the same level of access to an adequate internet connection or cellular services that make a virtual video visit possible? Telehealth needs to be adopted with equity in mind.” More

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    'Blinking' crystals may convert CO2 into fuels

    Imagine tiny crystals that “blink” like fireflies and can convert carbon dioxide, a key cause of climate change, into fuels.
    A Rutgers-led team has created ultra-small titanium dioxide crystals that exhibit unusual “blinking” behavior and may help to produce methane and other fuels, according to a study in the journal Angewandte Chemie. The crystals, also known as nanoparticles, stay charged for a long time and could benefit efforts to develop quantum computers.
    “Our findings are quite important and intriguing in a number of ways, and more research is needed to understand how these exotic crystals work and to fulfill their potential,” said senior author Tewodros (Teddy) Asefa, a professor in the Department of Chemistry and Chemical Biology in the School of Arts and Sciences at Rutgers University-New Brunswick. He’s also a professor in the Department of Chemical and Biochemical Engineering in the School of Engineering.
    More than 10 million metric tons of titanium dioxide are produced annually, making it one of the most widely used materials, the study notes. It is used in sunscreens, paints, cosmetics and varnishes, for example. It’s also used in the paper and pulp, plastic, fiber, rubber, food, glass and ceramic industries.
    The team of scientists and engineers discovered a new way to make extremely small titanium dioxide crystals. While it’s still unclear why the engineered crystals blink and research is ongoing, the “blinking” is believed to arise from single electrons trapped on titanium dioxide nanoparticles. At room temperature, electrons — surprisingly — stay trapped on nanoparticles for tens of seconds before escaping and then become trapped again and again in a continuous cycle.
    The crystals, which blink when exposed to a beam of electrons, could be useful for environmental cleanups, sensors, electronic devices and solar cells, and the research team will further explore their capabilities.

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